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Study identifier: NCT07104019 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Biofiller and Gingival Phenotype Thickening

Condition: Gingival Recession · Gingival Diseases · Gingival Inflammation  ·  Sponsor: Inonu University

PhaseNA
Planned participants34
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

The periodontal phenotype is defined as the combination of the gingival phenotype and the thickness of the buccal bone plate (bone morphotype). The gingival phenotype refers to the gingival thickness (GT) and the width of the keratinized tissue (KTW). A gingival thickness of ≤1 mm is classified as a thin phenotype, whereas a thickness \>1 mm is considered a thick phenotype. Thin gingival biotypes tend to show more pronounced responses to inflammation, restorations, trauma, and parafunctional habits. Various methods are used to assess gingival thickness, including transgingival probing (TP), ultrasonic measurements, cone-beam computed tomography (CBCT) scans, visual assessment, and colored biotype probes (CBP). Periodontal plastic procedures performed using autogenous grafts such as connective tissue grafts (CTG) and free gingival grafts (FGG), or biomaterials such as acellular dermal matrices (ADM) and collagen matrices (CM), are known to significantly increase GT and the amount of keratinized tissue. However, creating a second surgical site in the oral cavity during these procedures may compromise patient comfort, prompting researchers to explore alternative methods. Additionally, the effectiveness of synthetic biomaterials has been found to be lower than that of autogenous grafts. Platelet-rich concentrates have been used as a minimally invasive procedure for the past thirty years, showing a high capacity to release growth factors that support tissue regeneration. While pl…

This description comes directly from the study's public registry record.

Talk to the study team

Kubra Aral, PhD  ·  00903410106  ·  kubra.aral@inonu.edu.tr

Always discuss trial participation with your own doctor first.

Locations (1)

Inonu universityMalatya, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07104019