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Study identifier: NCT07103941 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

IOA Preventing Occlusal Changes With MAD Use

Condition: Sleep Related Breathing Disorder · Snoring · Obstructive Sleep Apnea (OSA)  ·  Sponsor: Isabel Moreno Hay

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes in how the teeth fit together, including the development of a posterior open bite. Participants in this study will be randomly assigned to one of two standard-of-care approaches: using an interocclusal aligner each morning after removing the MAD, or performing daily jaw exercises. Both methods aim to reduce the risk of occlusal changes. The study will follow participants over a 3-month period and includes dental evaluations, 3D oral scans, and short daily surveys. Findings from this research may help guide best practices for preserving occlusion during MAD therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Salma Habib, BDS  ·  8593235500  ·  skha265@uky.edu

Isabel Moreno Hay, MS, PhD  ·  8593235500  ·  orofacialpain@uky.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Orofacial Pain Center - University of Kentucky - Kentucky ClinicLexington, Kentucky, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07103941