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Study identifier: NCT07102641 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies

Condition: Cesarean Delivery · Postpartum Comfort · Postpartum Pain  ·  Sponsor: Thomas Jefferson University

PhasePhase 4
Planned participants825
Who can joinFemale, 16 Years to no upper limit
Healthy volunteersNo

About this study

Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are the preferred first-line therapies. There is no standard practice, however, on best dosing schedules (ie staggered or different time v. simultaneous or same time). This protocol describes a randomized clinical trial aimed to determine whether staggered dosing of acetaminophen and NSAIDs in superior to simultaneous dosing in controlling post-cesarean pain.

This description comes directly from the study's public registry record.

Talk to the study team

Whitney Bender, MD  ·  434-294-8416  ·  whitney.bender@jefferson.edu

Brandy Firman  ·  215-586-1656  ·  brandy.firman@jefferson.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Thomas Jefferson University HospitalPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07102641