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Study identifier: NCT07101939 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)

Condition: Obesity · Muscle Loss  ·  Sponsor: Actimed Therapeutics Ltd

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Semaglutide is approved for weight management (weight loss and weight maintenance) in adult obese patients. Drug treatments like semaglutide that result in weight-loss can also decrease muscle mass. The purpose of this study is to investigate the effect of ACM-001.1 (the study drug) on how much muscle is lost when a person takes it with semaglutide (PROACT 1) and how much muscle mass is gained when a person continues taking ACM-001.1 but stops taking semaglutide (PROACT 2).

This description comes directly from the study's public registry record.

Talk to the study team

Fabio Dorigotti, MD  ·  +41 79 653 55 67  ·  info@actimedtherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (7)

Clinical Hospital Center 'Dr Dragisa Misovic - Dedinje'Belgrade, SerbiaRecruiting
Clinical Hospital Center Bezanijska kosaBelgrade, SerbiaRecruiting
University Clinical Center of SerbiaBelgrade, SerbiaRecruiting
University Clinical Center KragujevacKragujevac, SerbiaRecruiting
Klinika Za Endocrinologiju, Dijabetes I Bolesti MetabolizmaNiš, SerbiaRecruiting
University Clinical Center of VojvodinaNovi Sad, SerbiaRecruiting
Opsta bolnica PancevoPančevo, SerbiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07101939