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Study identifier: NCT07101744 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Iparomlimab and Tuvonralimab Combined With Nimotuzumab in Recurrent or Metastatic NPC After First-line Treatment Failure: A Single-arm Phase IIa Clinical Trial

Condition: Nasopharyngeal Carcinoma (NPC) · First-line Treatment Failure Nasopharyngeal Carcinoma  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants41
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This study aims to preliminarily explore the efficacy and safety of Iparomlimab and Tuvonralimab in combination with Nimotuzumab for the treatment of recurrent/metastatic nasopharyngeal carcinoma (NPC). It is expected to investigate a novel therapeutic regimen with improved efficacy and enhanced safety for recurrent/metastatic NPC, thereby providing robust evidence-based medical support for the application of dual-target immune checkpoint inhibitors in nasopharyngeal carcinoma therapy

This description comes directly from the study's public registry record.

Talk to the study team

hui xiao wang, Ph.D. (Doctor of Philosophy)  ·  86+18826260661  ·  wangxh@sysucc.org.cn

fei han, Ph.D. (Doctor of Philosophy)  ·  86+13822113698  ·  hanfei@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07101744