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Study identifier: NCT07101497 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Trial of BN104 as Post-HSCT Maintenance in Acute Leukemia

Condition: Menin Inhibitors · Post Hematopoietic Stem Cell Transplantation · Maintenance Therapy  ·  Sponsor: The First Affiliated Hospital of Soochow University

PhasePhase 2
Planned participants60
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 2, open label, single arm trial. This study aims to assess the efficacy and safety of menin inhibitor BN104 as maintenance therapy in patients with acute leukemia harboring specific genetic alterations who have undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT). Eligible patients will be screened at 30-180 days post allo-HSCT. Participants will take BN104 100-200mg orally, twice a day, 28 days a cycle for 24-36 cycles. The primary endpoint is 2-year relapse-free survival rate since enrollment. The secondary endpoints included overall survival, event-free survival, cumulative incidence of relapse, non relpase related mortality and safety.

This description comes directly from the study's public registry record.

Talk to the study team

Su-ning Chen, M.D.  ·  (0086)13814881746  ·  chensuning@sina.com

Hai-ping Dai, M.D.  ·  (0086)13914086271

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Soochow UniversitySuzhou, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07101497