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Study identifier: NCT07100613 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus

Condition: Oral Lichen Planus · Oral Lichen Planus Related Stress · Oral Mucosal Disease  ·  Sponsor: University of Palermo

PhasePhase 2
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if a mucoadhesive patch containing clobetasol alone or in combination with resveratrol can reduce symptoms and improve quality of life in adults with Oral Lichen Planus (OLP). The main questions it aims to answer are: Does the patch reduce oral pain and burning sensations? Does it improve the appearance of oral lesions and patients' daily well-being? Researchers will compare: A patch containing clobetasol A patch containing clobetasol and resveratrol A standard clobetasol 0.05% ointment in an adhesive base Participants will: Apply their assigned treatment to the oral lesion daily for 30 days Attend three clinical visits for evaluations and imaging Complete questionnaires about pain, symptoms, and treatment experience

This description comes directly from the study's public registry record.

Talk to the study team

Vera Panzarella  ·  091 6554612  ·  vera.panzarella@unipa.it

Viviana De Caro  ·  09123891926  ·  viviana.decaro@unipa.it

Always discuss trial participation with your own doctor first.

Locations (1)

University of PalermoPalermo, Italy, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07100613