Condition: Gingival Inflammation · Dental Plaque · Atheroma Plaque · Sponsor: Istanbul Saglik Bilimleri University
Periodontitis is considered a focus of infection where oral bacteria, bacterial by-products or inflammatory mediators can interact with other parts of the organism via the blood. Periodontal pathogen components such as DNA, RNA or specific antigens of P. gingivalis, Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), Treponema denticola (T. denticola), Fusobacterium nucleatum (F. nucleatum) or Campylobacter rectus have been isolated from different tissues such as atheroma plaques, placenta, amniotic sac and respiratory tract. It has been reported that periodontitis may contribute to endothelial dysfunction leading to the formation of atherosclerosis.
This description comes directly from the study's public registry record.
Ayşe Toraman · 05385025422 · draysetoraman@gmail.com
Always discuss trial participation with your own doctor first.
| Health Sciences University, Hamidiye Faculty of Dentistry, Department of Periodontology | Istanbul, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07100574