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Study identifier: NCT07100457 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

OR6A2 on Monocytes and Cardiovascular Outcomes in Myocardial Ischemia-Reperfusion Injury

Condition: Myocardial Ischemia-Reperfusion Injury  ·  Sponsor: Southeast University, China

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

This study examines how the interaction between octanal (an OR6A2 receptor activator) and OR6A2 expression influences inflammation and clinical outcomes in Myocardial Ischemia-Reperfusion Injury patients. We analyze two key relationships: 1) The octanal-OR6A2 pathway's association with systemic oxidative stress/inflammatory biomarkers, and 2) How OR6A2 expression patterns on monocyte subtypes and plasma octanal levels correlate with major cardiovascular events. Patients undergoing this post-revascularization injury provided blood samples for OR6A2/octanal/inflammation measurements. IR Injury patients underwent 44-month clinical follow-up. Results may identify biological markers for personalized risk assessment after revascularization therapies. Ethics approval: Zhongda Hospital #2020ZDSYLL051-P01.

This description comes directly from the study's public registry record.

Talk to the study team

Wenbin Lu, PhD  ·  +86 13605185175  ·  101012092@seu.edu.cn

Yahao Zhang, M.D.  ·  +86 13523060936  ·  zhyh626@163.com

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Locations (1)

Department of Cardiology, Zhongda Hospital, Southeast UniversityNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07100457