Condition: Healthy Controls · Sponsor: Laureate Institute for Brain Research, Inc.
Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision. Following the results of a pilot study in which the investigators observed target engagement when LIFU was applied to the anterior limb of the internal capsule, the investigators now propose to determine the dose-response relationships of LIFU when applied to deep white matter tracts of the human brain. The investigators hope a successful study will be rapidly translatable into clinical trials seeking to understand mechanistic brain circuit-symptom relationships in major psychiatric disorders.
This description comes directly from the study's public registry record.
Salvador M Guinjoan, MD, PhD · 918-502-5119 · sguinjoan@laureateinstitute.org
Danielle E Clark, MA · 918-701-9610 · dclark@laureateinstitute.org
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| Laureate Institute for Brain Research | Tulsa, Oklahoma, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07099950