Condition: Rectal Cancer · Colon Cancer · Ovarian Cancer · Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle
Colorectal cancers and ovarian cancers are respectively the 2nd and 5th cause of cancer mortality in France. Surgical resection is a crucial step in the therapeutic management of colorectal cancers. For advanced ovarian cancers, the objective of cytoreductive surgery is to obtain complete macroscopic resection with no visible residual disease. One or more digestive resections are often required to achieve this goal of complete surgery (usually a modified posterior pelvic exenteration with colorectal resection). A ligation of the inferior mesenteric artery at its origin is classically performed in left colectomies and rectal resection for colorectal cancers. This allows the resection of the colorectal segment with a complete mesocolic lymphadenectomy until the origin of the inferior mesenteric artery and a good mobilization of the descending colon to allow its anastomosis to the underlying rectal stump. This ligation of the inferior mesenteric artery at its origin is also frequently performed in cases of modified posterior pelvic exenteration for ovarian cancer. Recently, several studies suggest that arterial ligation of the inferior mesenteric artery could be performed below the emergence of the left colic artery. Its preservation requiring a meticulous vascular dissection would allow a better vascularization of the descending colon and of the colorectal anastomosis without affecting the carcinologic quality of the resection and the number of resected lymph-nodes. Indeed, …
This description comes directly from the study's public registry record.
Aurore MOUSSION · 467613102 · aurore.moussion@icm.unicancer.fr
Pierre-Emmanuel COLOMBO, PHD · 467612401 · pierre-emmanuel.colombo@icm.unicancer.fr
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| Icm Val D'Aurelle | Montpellier, Herault, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07098182