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Study identifier: NCT07096674 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Condition: Narcolepsy Type 1 · Narcolepsy Type 2 · Idiopathic Hypersomnia  ·  Sponsor: Centessa Pharmaceuticals (UK) Limited

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study is a long-term extension (LTE) of the parent Study ORX750 0201, and will provide long-term open-label safety, tolerability, and efficacy of ORX750 in participants with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).

This description comes directly from the study's public registry record.

Talk to the study team

Orexin Centessa Program Lead  ·  617-468-5770  ·  ORX750-LTE@centessa.com

Always discuss trial participation with your own doctor first.

Locations (24)

Auburn, alabamaAuburn, Alabama, United StatesRecruiting
Santa Ana, CaliforniaSanta Ana, California, United StatesRecruiting
Miami, FloridaMiami, Florida, United StatesRecruiting
Orlando, FloridaOrlando, Florida, United StatesRecruiting
Winter Park, FLWinter Park, Florida, United StatesRecruiting
Stockbridge, GAAtlanta, Georgia, United StatesRecruiting
Atlanta, GeorgiaAtlanta, Georgia, United StatesRecruiting
Sterling Heights, MichiganSterling Heights, Michigan, United StatesRecruiting
Hendersen, NavadaHenderson, Nevada, United StatesRecruiting
Henderson, NevadaHenderson, Nevada, United StatesRecruiting
Denver, North CarolinaDenver, North Carolina, United StatesRecruiting
Huntersville, North CarolinaHuntersville, North Carolina, United StatesRecruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07096674