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Study identifier: NCT07096297 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Luspatercept + Darbepoetin in MDS

Condition: MDS (Myelodysplastic Syndrome)  ·  Sponsor: Yale University

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This is a single arm open-label Phase II trial of luspatercept and darbepoetin alfa in non-mutated SF3B1 , lower-risk, RBC transfusion dependent MDS participants with an endogenous erythropoietin (EPO) level \< 500 IU/L.

This description comes directly from the study's public registry record.

Talk to the study team

Stephanie Ladd  ·  9548950576  ·  stephanie.ladd@yale.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Yale UniversityNew Haven, Connecticut, United StatesRecruiting
Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicago, Illinois, United StatesNot Yet Recruiting
Harold C. Simmons Comprehensive Cancer Center of UT SouthwesternDallas, Texas, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07096297