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Study identifier: NCT07095517 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

Condition: Colorectal Cancer Prevention · Colorectal Adenoma  ·  Sponsor: Massachusetts General Hospital

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

This research study is an open-label Phase 1 Exploratory/Pilot clinical trial to measure the effects of the incretin mimetic, tirzepatide, on tissue, urine, blood, and microbiome biomarkers associated with colorectal cancer risk and to understand the feasibility of this precision prevention trial approach for a future larger study.

This description comes directly from the study's public registry record.

Talk to the study team

Andrew T. Chan, MD, MPH  ·  617-726-3212  ·  achan@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General Hospital Cancer CenterBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07095517