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Study identifier: NCT07094685 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer

Condition: Advanced Head and Neck Squamous Cell Carcinoma · Resectable Head and Neck Squamous Cell Carcinoma · Stage II Head and Neck Cutaneous Squamous Cell Carcinoma  ·  Sponsor: University of Michigan Rogel Cancer Center

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial tests how well ivonescimab before surgery works in treating patients with stage II-IV head and neck cancer that can be removed by surgery (resectable). Ivonescimab is a bispecific monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. A bispecific monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens).

This description comes directly from the study's public registry record.

Talk to the study team

Cancer AnswerLine  ·  1-800-865-1125  ·  CancerAnswerLine@med.umich.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Michigan Comprehensive Cancer CenterAnn Arbor, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07094685