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Study identifier: NCT07092813 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pharmacokinetics of Sulopenem Etzadroxil Plus Probenecid in Adolescents

Condition: Pharmacokinetics After Oral Intake  ·  Sponsor: Iterum Therapeutics, International Limited

PhasePhase 1
Planned participants12
Who can joinAll sexes, 12 Years to 17 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the use of sulopenem etzadroxil plus probenecid in adolescent patients being treated for bacterial infection. The main questions it aims to answer are: Is sulopenem etzadroxil plus probenecid safe to use in adolescents? Is sulopenem etzadroxil plus probenecid tolerable when used in adolescents? When ingested, what does the adolescent body do to sulopenem etzadroxil plus probenecid, in terms of the movement of the drug into, through, and out of the body. Participants will receive standard of care antibiotics for their bacterial infection as directed by their physician. In addition, participants will be asked to take a single oral dose of sulopenem etzadroxil plus probenecid. Blood samples will be collected before the dose of sulopenem etzadroxil plus probenecid, as well as at specified timepoints after the dose. Likewise, urine will be collected at specified time periods after the dose. During the course of the study, data will be collected from participants including vital sign measurements, physical examination findings, and the details of any adverse events that are reported.

This description comes directly from the study's public registry record.

Talk to the study team

Senior Vice President and Head of Clinical Development  ·  860-661-4035  ·  saronin@iterumtx.com

Always discuss trial participation with your own doctor first.

Locations (1)

Medical facilityLittle Rock, Arkansas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07092813