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Study identifier: NCT07091279 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

Condition: Autism Spectrum Disorder · Challenging Behaviour · Aggression  ·  Sponsor: Jeremy Veenstra-vanderweele

PhasePhase 2
Planned participants60
Who can joinAll sexes, 12 Years to 40 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors. Participants will be randomly assigned to receive either propranolol or a placebo (a look-alike substance that contains no drug) daily for 12 weeks. After the 12 weeks, all participants will have the opportunity to receive propranolol for an additional 12 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Suvekcha Bhattachan, MA  ·  914-997-5587  ·  suvekcha.bhattachan@nyspi.columbia.edu

Alyssa Verdes, BA  ·  914-997-5532  ·  alyssa.verdes@nyspi.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (2)

New York State Institute for Basic Research (IBR)Staten Island, New York, United StatesRecruiting
Center for Autism and the Developing BrainWhite Plains, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07091279