Condition: Advanced/Metastatic Solid Tumors · Bladder Cancer · Urothelial Carcinoma · Sponsor: Pfizer
The purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of the bladder, lung, head and neck, esophagus, or pancreas. PF-08046876 is an investigational anticancer therapy called an 'antibody drug conjugate' or 'ADC'. ADCs are anticancer drugs designed to stick to cancer cells and kill them. The study drug will be given to participants through a needle in a vein (intravenous infusion). This study includes multiple parts. In the first part of the study, there will be different groups of people receiving different doses of the study drug. The study may also test different schedules.
This description comes directly from the study's public registry record.
Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com
Always discuss trial participation with your own doctor first.
| City of Hope National Medical Center | Duarte, California, United States | Recruiting |
| City of Hope at Irvine Lennar | Irvine, California, United States | Recruiting |
| Ronald Reagan UCLA Medical Center | Los Angeles, California, United States | Not Yet Recruiting |
| UCLA Department of Medicine-Hematology/Oncology | Los Angeles, California, United States | Not Yet Recruiting |
| Santa Monica UCLA Medical Center & Orthopaedic Hospital | Santa Monica, California, United States | Not Yet Recruiting |
| UCLA Hematology/Oncology - Santa Monica | Santa Monica, California, United States | Not Yet Recruiting |
| Smilow Cancer Hospital - Yale New Haven Health | New Haven, Connecticut, United States | Recruiting |
| Yale - New Haven Hospital - Yale Cancer Center | New Haven, Connecticut, United States | Recruiting |
| Smilow Cancer Hospital Phase 1 Unit | New Haven, Connecticut, United States | Recruiting |
| Smilow Cancer Hospital - Trumbull | Trumbull, Connecticut, United States | Recruiting |
| Brigham and Women's Hospital | Boston, Massachusetts, United States | Recruiting |
| Dana-Farber Cancer Institute | Boston, Massachusetts, United States | Recruiting |
+ 18 more locations — full list on the registry record.
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07090499