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Study identifier: NCT07089550 Synced from ClinicalTrials.gov · July 28, 2026
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PSMA PET for Treatment Response evaLuation of systemIC Therapies in prostAte caNcer (PELICAN)

Condition: PSMA Positive Tumors or Tumor Tissues · Prostate Cancer Metastatic  ·  Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna

PhaseN/A
Planned participants1300
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective clinical study aims to evaluate the predictive power of PSMA PET imaging in patients with advanced prostate cancer who are receiving systemic drug therapies. The primary goal is to identify prognostic factors derived from PSMA PET imaging. These factors include the number of cancer lesions, the size of the tumor, and measurements known as SUVmax and SUVmean. By identifying these factors, the investigators aim to better group patients and predict those who may have a less favorable outcome. While PSMA PET imaging is highly accurate in locating cancer sites within the body, its ability to predict treatment response has not yet been thoroughly studied in a prospective manner for this patient population. This study will assess the predictive role of PSMA PET imaging and its ability to forecast treatment response across a range of systemic therapies, including hormone therapy and chemotherapy, in patients with both hormone-sensitive (HSPC) and castration-resistant (CRPC) prostate cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea Farolfi, MD  ·  +390512143959  ·  andrea.farolfi@aosp.bo.it

Andrea Di Giorgio, MD  ·  +390512143959  ·  andrea.digiorgio@live.it

Always discuss trial participation with your own doctor first.

Locations (4)

Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di BolognaBologna, Italy, ItalyRecruiting
Azienda Ospedaliera Santa Croce e Carle - ospedale Santa CroceCuneo, Italy, ItalyRecruiting
U.O. Medicina Nucleare, IRCCS Ospedale Policlinico San MartinoGenova, Italy, ItalyRecruiting
UOC Medicina Nucleare, AOU Policlinico G.MartinoMessina, Italy, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07089550