Condition: Chronic Cough (CC) · Asthma · Sponsor: McMaster University
The inhalation of adenosine 5'-triphosphate (ATP) to evoke cough (ATP cough challenge) is becoming increasingly used as a tool to measure cough hypersensitivity in patients with chronic cough. However, the safety, feasibility, and repeatability of this procedure is not widely known. In this study, we will perform ATP cough challenges in healthy individuals and in patients with mild asthma and chronic cough to better understand the safety, feasibility, and repeatability of these challenges. Such information will guide the future conduct of ATP cough challenges to measure cough hypersensitivity and identify patients who may better respond to ATP-blocking therapies.
This description comes directly from the study's public registry record.
Imran Satia, MD PhD · 905-525-2100 · satiai@mcmaster.ca
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| Respiratory Research Lab | Hamilton, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07085975