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Study identifier: NCT07085377 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Autonomous Methadone Delivery System by Nurses

Condition: Opioid Use Disorder (OUD) · Addictology  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants182
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Initiations of methadone treatment for opiode use disorder (OUD) are carried out in France in specialized centers, known as centers for care, support and prevention in addictology (CSAPA) In this way, hospital practitioners initiate the prescription of methadone, which is delivered on the spot by the nursing team. CSAPA nurses, and addictology nurses more generally, have a real range of skills which can include adapting treatment doses according to a protocol pre-established in a team, and medically validated (French law no. 2019-774 of July 24, 2019 relating to the organization and transformation of the healthcare system). The methadone speciality used for initiation in CSAPAs is almost always the syrup form. The capsule form can only be used after one year's treatment, unless exceptionally authorized by the medical officer of the French National Health Insurance Fund. However, regulations stipulate that the prescription of methadone syrup must be renewed every fourteen days, which in theory means that a CSAPA doctor must see the patient at least twice a month to renew the prescription, throughout the entire course of treatment. In practice, medical resources are often not sufficient for patients to be seen by a doctor at such a rate. Numerous palliative organizations exist, though they remain poorly described and documented. In some centers, doctors focus primarily on initiations, and prescriptions for patients for whom "stability" has been achieved are sometimes renewed …

This description comes directly from the study's public registry record.

Talk to the study team

Benjamin ROLLAND, MD  ·  4 37 915 072  ·  Benjamin.rolland@chu-lyon.fr

William COSTES, Nurse  ·  437117 852  ·  William.costes@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (8)

CSAPA, Association Bizia, Centre Hospitalier de la Côte BasqueBayonne, FranceNot Yet Recruiting
CSAPA, Service d'Addictologie, Centre Hospitalier Charles Perrens, CHU de BordeauxBordeaux, FranceNot Yet Recruiting
CSAPA de BrioudeBrioude, FranceNot Yet Recruiting
CSAPA, Association Nationale de Prévention en Alcoologie et Addictologie (ANPAA), Résidence Le Victor HugoLe Puy-en-Velay, FranceNot Yet Recruiting
CSAPA, Service Universitaire d'Addictologie de Lyon, Hôpital Edouard Herriot, Hospices Civils de LyonLyon, FranceRecruiting
CSAPA, Hôpital de la Croix Rousse, Hospices Civils de LyonLyon, FranceNot Yet Recruiting
CSAPA, Service de Psychiatrie et d'Addictologie, Hôpital Civil, CHRU de StrasbourgStrasbourg, FranceNot Yet Recruiting
CSAPA du Griffon, Oppelia Aria 69Villeurbanne, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07085377