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Study identifier: NCT07085169 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Low-dose Trifluridine/Tipiracil With Bevacizumab in mCRC

Condition: Colo-rectal Cancer · Third-line and Beyond Therapy · TAS 102  ·  Sponsor: Ruijin Hospital

PhasePhase 2
Planned participants50
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase II, single-center, prospective trial aimed to investigate the efficacy and safety of a modified regimen of trifluridine/tipiracil plus bevacizumab in refractory metastatic colorectal cancer. Patients will be treated with trifluridine/tipiracil (17.5 mg/m2 dose orally twice daily, d1-10, every 14-days) plus bevacizumab (5mg/kg dose intravenously once at day 1, every 14-days). The study treatment will be administered until progression of disease, intolerable toxicity or withdraw of consent.

This description comes directly from the study's public registry record.

Talk to the study team

Chen-Fei Zhou, MD, Ph.D  ·  +86-21-64370045  ·  zcf12085@rjh.com.cn

Always discuss trial participation with your own doctor first.

Locations (2)

SanMing First HospitalSanming, ChinaRecruiting
Ruijin HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07085169