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Study identifier: NCT07082920 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

Condition: Prostatic Neoplasms  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 1
Planned participants140
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify the recommended phase 2 combination dose (RP2CD) of JNJ-78278343 in combination with JNJ-95298177 in Part 1 (Dose confirmation) of the study and to determine how safe and tolerable the RP2CD is for treatment of participants with metastatic castration-resistant prostate cancer (mCRPC; a stage of prostate cancer where the cancer has spread beyond the prostate and is resistant to hormonal therapy) in Part 2 (Dose expansion) of study.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (6)

Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Columbia University Medical CenterNew York, New York, United StatesRecruiting
University Hospitals Cleveland Medical CenterCleveland, Ohio, United StatesRecruiting
Fred Hutchinson Cancer CenterSeattle, Washington, United StatesRecruiting
The Christie Nhs Foundation TrustManchester, United KingdomRecruiting
Royal Marsden Hospital (Sutton)Sutton, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07082920