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Study identifier: NCT07082868 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

Condition: Primary Central Nervous System Lymphoma (PCNSL) · Primary Central Nervous System Lymphoma · Relapsed Primary Central Nervous System Lymphoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1
Planned participants26
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find out whether the combination of epcoritamab and ibrutinib is a safe treatment approach that causes few or mild side effects in people with relapsed/refractory primary central nervous system lymphoma (PCNSL) or secondary central nervous system lymphoma (SCNSL).

This description comes directly from the study's public registry record.

Talk to the study team

Christian Grommes, MD  ·  212-610-0344  ·  grommesc@mskcc.org

Lauren Schaff, MD  ·  212-610-0485  ·  schaffl@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (8)

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting
University of Utah (Data Collection Only)Salt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07082868