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Study identifier: NCT07081984 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors

Condition: HPV 16+ Recurrent or Metastatic Cancer · HNSCC · Cervical Cancer  ·  Sponsor: Therorna

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a phase I, open-label, dose escalation study to assess the safety, tolerability, efficacy and immunogenicity of TI-0093 injection in patients with recurrent or metastatic HPV-16 positive solid tumors. The primary objectives of the study are to assess safety and tolerability of TI-0093 injection in patients with recurrent or metastatic solid tumors, and to determine the maximum tolerated doses (MTDs) and recommended Phase 2 doses (RP2Ds) of TI-0093 injection.

This description comes directly from the study's public registry record.

Talk to the study team

Ye Guo  ·  0086-457-13501678472  ·  pattrickguo@gmail.com

The Drug Clinical Trial Institution of Shanghai East Hospital  ·  021-38804518-28329  ·  shdfgcp@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai East HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07081984