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Study identifier: NCT07080892 Synced from ClinicalTrials.gov · July 28, 2026
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The Effect of Distal Versus Proximal iPACK on Pain After Total Knee Arthroplasty

Condition: Postoperative Pain Following Knee Arthroplasty  ·  Sponsor: Comenius University

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Total knee arthroplasty (TKA) often results in significant postoperative pain, which can hinder recovery despite advances in surgical and anesthetic techniques. Traditional pain management methods like femoral nerve blocks may impair motor function, delaying rehabilitation. The iPACK block, targeting the posterior knee without affecting motor control, offers a promising alternative. This study aims to compare the effectiveness of two iPACK block approaches-proximal (at the distal femoral shaft) and distal (between the femoral condyles)-in managing postoperative pain in TKA patients. In a double-blind, randomized controlled trial with 120 participants, pain scores, opioid use, and time to rescue analgesia will be assessed. The hypothesis is that the distal iPACK block provides superior pain relief, potentially improving patient outcomes and recovery.

This description comes directly from the study's public registry record.

Talk to the study team

Andrej Dano, MD  ·  +421911571616  ·  danoandreas@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

1st Department of Anaesthesiology and Intensive Care MedicineBratislava, SlovakiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07080892