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Study identifier: NCT07079462 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparing 18F-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis

Condition: Colorectal Cancer · Peritoneal (Metastatic) Cancer · FAPI PET  ·  Sponsor: Fudan University

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Main objective: 1\. To compare the objective response rate (ORR) of 18F-FAPI PET-guided abdominal region radiotherapy combined with second-line standard treatment versus cabozantinib and second-line standard treatment in the treatment of peritoneal metastasis of colorectal cancer. Secondary objectives: 1. To compare the disease control rate (DCR), duration of continuous remission (DoR), progression-free survival (PFS) and overall survival (OS) of 18F-FAPI PET-guided abdominal region radiotherapy combined with second-line standard treatment versus cabozantinib and second-line standard treatment in the treatment of peritoneal metastasis of colorectal cancer. 2. To evaluate the safety and tolerability of 18F-FAPI PET-guided abdominal region radiotherapy combined with second-line standard treatment versus cabozantinib.

This description comes directly from the study's public registry record.

Talk to the study team

Guoxiang Cai  ·  086-18017312703  ·  gxcaifuscc@163.com

Always discuss trial participation with your own doctor first.

Locations (2)

Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting
Fudan University Shanghai Cancer CenterShanghai, ChinaCompleted

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Source record: clinicaltrials.gov/study/NCT07079462