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Study identifier: NCT07078877 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Low-Level Laser Therapy in Knee Osteoarthritis: Effects on Clinical Outcomes, Femoral Cartilage Thickness and Regional Sarcopenia

Condition: Knee Osteoarthritis · Low Level Laser Therapy · Regional Sarcopenia  ·  Sponsor: Ankara Etlik City Hospital

PhaseNA
Planned participants62
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

It was designed as a single-center, prospective, randomized controlled study. The study consists of two groups. Both groups of patients will receive a conventional home based exercise program. In addition to the conventional exercise program, patients in the first group will also receive low-level laser therapy (LLLT). If the laser group is found to be superior at the end of the study, the patients who only received the exercise program will be recalled and administered LLLT. Patients who meet the inclusion criteria will be enrolled in the study. Sample size calculations were based on data from a previous study by Alghadir et al. Using a mean of 3.25 and a standard deviation of 2.61 for the WOMAC pain subscale, the number of participants was calculated with 95% power and a 5% significance level. As a result, it was determined that at least 29 patients would be included in each group. Written informed consent will be obtained from each patient before enrollment. Randomization will be performed according to the order of patient admissions. Patients will be evaluated before treatment, and at the 1st and 3rd months post-treatment. The dosage of laser application was selected based on the recommendations of the World Association for Photobiomodulation Therapy (WALT). Patients will be treated 5 sessions per week for 2 weeks. The treatment will be applied using the BTL SMART 4000 laser device at a wavelength of 835 nm and a dose of 10 J/point. The conventional home based exercis…

This description comes directly from the study's public registry record.

Talk to the study team

IREM ADIGUZEL, MEDİCAL DOCTOR  ·  +90 505 443 14 45  ·  altinsoyyirem@gmail.com

OZGUR Z KARAAHMET, MEDİCAL DOCTOR  ·  +90 505 815 15 85  ·  drozguroz@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ankara Etlik City HospitalAnkara, YENIMAHALLE, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07078877