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Study identifier: NCT07078201 Synced from ClinicalTrials.gov · July 29, 2026
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Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl

Condition: Spinal Anesthesia Duration  ·  Sponsor: Nashwa Ahmed

PhasePhase 4
Planned participants40
Who can joinAll sexes, 20 Years to 60 Years
Healthy volunteersNo

About this study

Spinal anesthesia is the most widely employed procedure for lower limb orthopedic operations, as it is very cost-effective and simple to apply. These advantages could be restricted because presently existing local anesthetic drugs had relatively short length of action. (1) Spinal anesthesia with 0.5% heavy bupivacaine (hyperbaric) is a common technique, still there was burden of its short duration of action. To overcome this issue, there was a continuous search for an ideal adjuvant.(2) Adjuvants were mostly added to local anesthetic drugs to increase their effectiveness, speedy onset, increase the period of the block, and reduce the local anesthetics dosage, thus reduction their adverse effects.(3) Such adjuvants had been beneficial in extension of analgesia along with initiation of movement though their related side effects.(4)

This description comes directly from the study's public registry record.

Talk to the study team

Nashwa gomaa Ahmed, MD  ·  00201005289328  ·  dr_nashwa_2008@yahoo.com

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Locations (1)

Port said universityPort Said, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07078201