Condition: Upper Urinary Tract Urothelial Carcinoma · Sponsor: Zealand University Hospital
This is a study looking at how patients with a rare type of cancer in the pelvis and ureter of the kidney - called upper urinary tract urothelial carcinoma (UTUC) - is currently treated. The gold standard treatment of UTUC is the complete removal of the kidney, renal pelvis and ureter. The use of kidney-sparing surgery, which preserves the kidney while treating the cancer, was only considered for patients who were too frail to undergo kidney removal, had a solitary functioning kidney, or suffered from severe chronic kidney disease. Since 2018 international guidelines have incorporated kidney sparing surgery for all patients but only offered to patients that have been diagnosed with very low risk tumors to ensure the safety of the patients. The latest update of the UTUC Guidelines from the European Association of Urology has revised the criteria, so that certain features previously classified as high-risk are no longer considered high-risk on their own, provided the tumor otherwise appears benign. Nonetheless, ongoing research is essential to support this evolving approach and to further enhance the guidelines. Kidney sparing surgery comprise of a strict follow up schedule that often demands supplemental surgeries under general anesthesia, which can cause strain on patients. Preservation of the kidney is important since a decrease in kidney function can result in increased risk of cardiovascular disease and death. The main question we want to answer is: Can more patients w…
This description comes directly from the study's public registry record.
Juan L Vásquez, MD, PhD · +45 28947015 · julv@regionsjaelland.dk
Stine H Reeler, MD · +45 23428443 · sfhe@regionsjaelland.dk
Always discuss trial participation with your own doctor first.
| Department of Urology Aarhus University Hospital | Aarhus N, Denmark | Not Yet Recruiting |
| Herlev Gentofte Hospital | Herlev, Denmark | Not Yet Recruiting |
| Department of Urology, Copenhagen University Hospital - Rigshospitalet | København Ø, Denmark | Not Yet Recruiting |
| Department of Urology, Zealand University Hospital | Roskilde, Denmark | Recruiting |
| Haukeland University Hospital | Bergen, Norway | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07077447