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Study identifier: NCT07073365 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Bolstering Outcomes After Induction With Osimertinib Plus Chemotherapy Through Optimized Site-Directed Primary Tumor Therapy (BOOST Trial)

Condition: Non-Small Cell Lung Cancer · Epidermal Growth Factor Receptor  ·  Sponsor: Pusan National University Hospital

PhasePhase 2
Planned participants70
Who can joinAll sexes, 20 Years to no upper limit
Healthy volunteersNo

About this study

This is a single-arm, open-label, phase II study evaluating the clinical outcomes of local therapy (surgery or radiotherapy) to the primary tumor in patients with EGFR-mutant advanced non-small cell lung cancer (NSCLC) who have achieved disease control following first-line treatment with the FLAURA2 regimen (osimertinib plus platinum-based chemotherapy). The primary objective is to assess the median progression-free survival (PFS) after local therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Mi-Hyun Kim  ·  82-51-240-7845  ·  mihyunkim@pusan.ac.kr

Soo Han Kim  ·  82-51-240-7845  ·  kshyjt1004@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Pusan National University HospitalBusan, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07073365