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Study identifier: NCT07073079 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Assess the Effectiveness of Second-Line Therapy of Upadacitinib and Risankizumab in Adult Participants With Crohn's Disease in a Real-World Setting

Condition: Crohn's Disease  ·  Sponsor: AbbVie

PhaseN/A
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will evaluate the second line effectiveness of upadacitinib and risankizumab in Crohn's Disease (CD) in a real-world setting. Upadacitinib and risankizumab are approved drugs for treating CD. Approximately 250 participants who are prescribed upadacitinib or risankizumab by their physician in accordance with local label will be enrolled in 25 sites across Italy. Participants will receive upadacitinib or risankizumab as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 18 months. No additional burden for participants in this trial is expected.

This description comes directly from the study's public registry record.

Talk to the study team

Caterina Golotta  ·  +39 06 548891  ·  caterina.golotta@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (25)

Ospedale Specializzato In Gastroenterologia Saverio De Bellis /ID# 275706Castellana Grotte, Bari, ItalyRecruiting
Azienda Ospedaliero Universitaria di Cagliari - P.O. Duilio Casula /ID# 275216Monserrato, Cagliari, ItalyRecruiting
Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 275669San Giovanni Rotondo, Foggia, ItalyRecruiting
IRCCS Istituto Clinico Humanitas /ID# 274489Rozzano, Lombardy, ItalyRecruiting
IRCCS Ospedale San Raffaele /ID# 274458Milan, Milano, ItalyRecruiting
Fondazione IRCCS San Gerardo dei Tintori - Ospedale San Gerardo /ID# 274682Monza, Monza E Brianza, ItalyRecruiting
Azienda Ospedaliera Universitaria Federico II - Naples /ID# 274570Naples, Napoli, ItalyRecruiting
Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 274788Naples, Napoli, ItalyRecruiting
A.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 274461Turin, Piedmont, ItalyRecruiting
Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 274654Rome, Roma, ItalyRecruiting
Ospedale Sandro Pertini /ID# 275023Rome, Roma, ItalyRecruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 274530Rome, Roma, ItalyRecruiting

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07073079