Condition: Refractory Chronic Cough · Unexplained Chronic Cough · Cough Hypersensitivity · Sponsor: Hyfe Inc
The goal of this single-cohort clinical trial is to learn whether a smartphone-based Cough Management (CM) program can reduce cough frequency and burden in adults (21-80 years) who have refractory or unexplained chronic cough.  The main questions it aims to answer are: * Does four weeks of using the CM feature in the CoughPro app lower objective cough rate (coughs per hour) compared with each participant's one-week baseline?  * Does the program also lessen cough intensity (bout metrics) and improve patient-reported quality-of-life scores on the Leicester Cough Questionnaire and PGI-S? Participants will: * Wear a Hyfe CoughMonitor smartwatch continuously for 6 weeks (1-week baseline, 4-week intervention, 1-week follow-up), charging it nightly.  * Complete science-based in-app CM lessons based on behavioral cough-suppression therapy and practice the techniques during the 4-week intervention. * Fill out online questionnaires (LCQ and PGI-S) at baseline and at the end of Week 4. * Join a brief exit interview, then return the smartwatch and receive a compensation voucher.
This description comes directly from the study's public registry record.
Laurie Slovarp, PhD, CCC-SLP · 302-618-2348 · study@hyfe.com
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| Hyfe Inc. | Wilmington, Delaware, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07070895