← Eichor
Study identifier: NCT07069699 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

Condition: Burkitt Lymphoma · Double-Expressor Lymphoma · High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase Ib/II trial tests the safety, side effects, best dose and how well giving CX-5461 works for the treatment of patients with B-cell non-Hodgkin lymphoma. CX-5461 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving CX-5461 may be safe, tolerable and/or effective in treating patients with B-cell non-Hodgkin lymphoma.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (8)

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, California, United StatesRecruiting
UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, California, United StatesRecruiting
University of Kansas Clinical Research CenterFairway, Kansas, United StatesRecruiting
University of Kansas Cancer CenterKansas City, Kansas, United StatesRecruiting
University of Kansas Hospital-Indian Creek CampusOverland Park, Kansas, United StatesRecruiting
University of Kansas Hospital-Westwood Cancer CenterWestwood, Kansas, United StatesRecruiting
University of Oklahoma Health Sciences CenterOklahoma City, Oklahoma, United StatesRecruiting
University of Pittsburgh Cancer Institute (UPCI)Pittsburgh, Pennsylvania, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07069699