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Study identifier: NCT07068191 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly

Condition: Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD) · Hepatomegaly · Nonalcoholic Fatty Liver (NAFL)  ·  Sponsor: Phenomen Pharma

PhaseNA
Planned participants90
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study compares the effectiveness of the dietary supplement Gepaktiv with standard medications (UDCA and Ademetionine) in patients with fatty liver disease (MAFLD) and liver enlargement (hepatomegaly). Key points: * Participants will receive either Gepaktiv, UDCA, or Ademetionine for 15 days * Doctors will monitor liver health through blood tests and ultrasound scans * The study will check if Gepaktiv helps improve liver function as effectively as standard treatments. Main measurements: * Changes in liver enzyme levels (ALT, AST) * Reduction in liver size * Improvement in fat accumulation (steatosis) measured by FibroScan This research may provide evidence for a new natural option to support liver health.Data analysis will be done by an independent biostatistics

This description comes directly from the study's public registry record.

Talk to the study team

Evgeniy Chesnokov, MD, Professor  ·  +79091846111  ·  e.v.chesnokov@mail.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Tyumen State Medical UniversityTyumen, Tyumen Oblast, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07068191