Condition: ALS (Amyotrophic Lateral Sclerosis) · Sponsor: Chulalongkorn University
Motor neuron disease (MND) is a progressive neurological disorder involving degeneration of motor neurons, leading to muscle weakness, speech and swallowing difficulties, and respiratory failure. This study aims to develop a novel treatment approach combining personalized repetitive transcranial magnetic stimulation (rTMS) with mixed reality (MR) exercise-based games (exergames) to slow disease progression and improve quality of life. In this randomised controlled trial study will compare three groups: (1) rTMS with MR exercise (personalized intervention), (2) rTMS with MR exercise (standard intervention), and (3) sham rTMS with MR exercise. Outcomes will be assessed at baseline, 3 months, and 6 months post intervention. The long-term goal is to implement this approach in clinical settings to enhance care for people with MND.
This description comes directly from the study's public registry record.
Jakkrit Amornvit, MD · Thailand: 88-951-9195 · jakkrit.a@chula.ac.th
Phunsuk Kantha, PT.,PhD · Thailand: 93-295-1646 · phunsuk.kan@mahidol.ac.th
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| King Chulalongkorn Memorial hospital, The Thai Red Cross Society | Bangkok, Pathumwan, Thailand | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07067229