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Study identifier: NCT07066995 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer

Condition: Pancreatic Cancer · Pancreatic Carcinoma · Pancreatic Cancer Non-resectable  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants60
Who can joinAll sexes, 21 Years to 90 Years
Healthy volunteersNo

About this study

Autologous T-cells engineered to express CARs targeting Mesothelin and Claudin18.2, for Unresectable locally advanced or metastatic pancreatic adenocarcinoma (Pancreatic Ductal Adenocarcinoma, PDAC), administered as two separate sequential infusions following lymphodepleting chemotherapy

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, Phd  ·  +12077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07066995