Condition: Female Infertility · Oocyte Competence · Mitochondria · Sponsor: Sunkaky Medical Cooperation
The purpose of this study is to investigate the potential of autologous adipose stem cell (ASC) mitochondrial transfer (ASCENT) to oocytes along with intracytoplasmic sperm injection (ICSI)as a means of enhancing embryo development and improving the success rate of in patients with a history of multiple IVF failures. Embryo quality plays a crucial role in determining the success of assisted reproductive technologies and directly contributes to repeated pregnancy failures. Several factors, including age, physiological conditions, genetics, and environmental influences, can significantly impact embryo quality. Oocytes, the largest cells in the human body, are heavily reliant on mitochondria. Mitochondria's role in providing energy for oocytes is crucial, and insufficient energy production has been linked to poor oocyte and embryo quality. Some human studies have shown that increasing oocyte mitochondrial mass can improve embryo quality in patients who have experienced repeated IVF failures.
This description comes directly from the study's public registry record.
Dr. SANATHUDAYANGA KANKANAMGAMAGE, PhD · +818014361766 · udayanga646@ivfjapan.com
Dr. HELARUWAN PASAN KUMARA WA, MD, PhD · +94 77 327 3866, +9477 478 878 · helaruwanpasankumara@gmail.com
Always discuss trial participation with your own doctor first.
| Wish Fertility Hospital Pvt. Ltd | Colombo, Sri Lanka | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07066267