● Recruiting

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

Condition: Major Depressive Disorder (MDD) · Major Depressive Disorder With Anxious Distress · Sponsor: Seaport Therapeutics

PhasePhase 2

Planned participants360

Who can joinAll sexes, 18 Years to 65 Years

Healthy volunteersNo

About this study

This is a randomized, parallel-group, double-blind, placebo-controlled, monotherapy study to evaluate the efficacy, safety, and tolerability of SPT-300 (GlyphAllo) in adults with major depressive disorder (MDD), with or without anxious distress.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical trial information desk · 617-807-4062 · clinicaltrials@seaporttx.com

Always discuss trial participation with your own doctor first.

Locations (61)

Seaport Investigator Site	Chino, California, United States	Recruiting
Seaport Investigator Site	Garden Grove, California, United States	Recruiting
Seaport Investigator Site	Glendale, California, United States	Recruiting
Seaport Investigator Site	Redlands, California, United States	Recruiting
Seaport Investigator Site	San Jose, California, United States	Recruiting
Seaport Investigator Site	Cromwell, Connecticut, United States	Recruiting
Seaport Investigator Site	Jacksonville, Florida, United States	Recruiting
Seaport Investigator Site	Lauderhill, Florida, United States	Recruiting
Seaport Investigator Site	Orlando, Florida, United States	Recruiting
Seaport Investigator Site	Palm Bay, Florida, United States	Recruiting
Seaport Investigator Site	West Palm Beach, Florida, United States	Recruiting
Seaport Investigator Site	Atlanta, Georgia, United States	Recruiting

+ 49 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07065240