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Study identifier: NCT07064018 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

Condition: Soft-tissue Sarcoma · Triple Negative Breast Cancer · Non-small Cell Lung Cancer  ·  Sponsor: University of California, Irvine

PhasePhase 1/Phase 2
Planned participants67
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1b/IIa dose escalation clinical trial determining the recommended phase II dose of SPEDOX-6 in subjects with advanced, therapy-refractory soft-tissue sarcoma (STS); triple-negative breast cancer (TNBC); Non-small cell lung cancer (NSCLC); cervical cancer; ovarian cancer; KRAS mutant pancreatic ductal adenocarcinoma. These are subjects who have not previously been treated with anthracyclines.

This description comes directly from the study's public registry record.

Talk to the study team

Chao Family Comprehensive Cancer Center University of California, Irvine  ·  1-877-827-8839  ·  ucstudy@uci.edu

University of California Irvine Medical Center

Always discuss trial participation with your own doctor first.

Locations (1)

Chao Family Comprehensive Cancer Center University of California, IrvineOrange, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07064018