Condition: Esophagus Cancer · Sponsor: Central South University
This observational study aims to investigate a clinical cohort of patients with locally advanced esophageal cancer undergoing neoadjuvant chemoimmunotherapy. By integrating multimodal clinical data-including demographic characteristics, medical history, imaging studies, pathological findings, and laboratory tests-and employing deep learning algorithms, the study seeks to develop predictive models for the early and accurate assessment of treatment response prior to surgery. Specifically, this study focuses on addressing the following key scientific questions: 1. Can multimodal clinical data be used to construct an accurate model for predicting pathological complete response (pCR) following neoadjuvant therapy? 2. Can deep learning models enable early identification of patients with suboptimal response to neoadjuvant therapy, defined as stable disease (SD) or progressive disease (PD), before surgery?
This description comes directly from the study's public registry record.
Chen Chen · +8673185295188 · chenchen1981412@csu.edu.cn
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| The Second Xiangya Hospital of Central South University | Changsha, Hunan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07063901