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Study identifier: NCT07063446 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

Condition: Hemiplegia · Perinatal Brain Injury  ·  Sponsor: Medical University of South Carolina

PhaseNA
Planned participants10
Who can joinAll sexes, 8 Months to 24 Months
Healthy volunteersNo

About this study

Preterm and term infants with brain injury frequently have delayed motor skills, and one hand and arm may become stronger than the other, which can signal early cerebral palsy. A new treatment, transcutaneous vagus nerve stimulation (taVNS), boosts specific brain circuits and may improve function when paired with intensive motor activities. This study will test taVNS-paired constraint induced movement therapy in infants who have greater weakness on one side and determine if a single pulse of transcranial brain stimulation over the motor area can cause a measurable movement of the hand or thumb, and indicate which infants can benefit from 40h taVNS-paired CIMT.

This description comes directly from the study's public registry record.

Talk to the study team

Dorothea Jenkins, MD  ·  843-792-2112  ·  jenkd@mus.edu

Cynthia Dodds, PT PhD  ·  843- 792-5731  ·  doddscb@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07063446