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Study identifier: NCT07061704 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Oncolytic Virus in Esophageal Squamous Cell Carcinoma

Condition: Esophageal Cancer  ·  Sponsor: Sichuan University

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This clinical trial is designed to evaluate the preliminary efficacy and safety of an oncolytic virus combined with chemotherapy and an immune checkpoint inhibitor in patients with initially unresectable, locally advanced esophageal squamous cell carcinoma (ESCC). The primary endpoints are safety, surgical conversion rate and event-free survival (EFS). Secondary endpoints include overall survival (OS), objective response rate (ORR), and quality of life (QoL). Exploratory endpoints include biomarker analyses such as single-cell sequencing.

This description comes directly from the study's public registry record.

Talk to the study team

Zhenyu Ding, MD  ·  +862885422562  ·  dingzhenyu@scu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

West China Hospital of Sichuan UniversityChengdu, Sichuan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07061704