Condition: Hematopoietic Stem Cell Transplantation (HSCT) · Pulmonary Rehabilitation · Inspiratory Muscle Training · Sponsor: Ceren Derya Gültekin
Introduction: After haematopoietic stem cell transplantation (HSCT), patients often experience complications such as respiratory difficulties, fatigue and decreased quality of life. The aim of the study was to compare the effectiveness of different inspiratory muscle training (IMT) protocols on respiratory muscle strength and endurance, dyspnoea, maximal exercise capacity, diaphragmatic function, respiratory function parameters, peripheral muscle strength, fatigue, quality of life, oxidative stress parameters, muscle biomarkers and inflammatory biomarkers in HSCT recipients during the transplantation process. Method: The study will include patients between 18-65 years of age, who are able to walk and understand the instructions, who do not have orthopedic, neurological or cardiac disorders and who will undergo haematopoietic stem cell transplantation. Patients with cognitive impairments; orthopedic or neurological diseases that may affect the evaluation of physical fitness tests; patients with comorbidities such as asthma, COPD will not be included in the study. In cases where the exercise group subjects' attendance to the training protocol is interrupted for 3 sessions or more consecutively, the voluntariness to participate in the research is lost during the research process, and clinical haemodynamic instability develops in the subjects, the participant will be excluded from the study. Patients in whom exercise training is contraindicated such as acute bleeding, haemoglob…
This description comes directly from the study's public registry record.
Ceren Derya Gültekin, MSc · +905383200141 · cerenderya1@gmail.com
Mine Gülden Polat, Professor · +905325136861 · gpolat@marmara.edu.tr
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| Istinye University | Istanbul, Zeytinburnu, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07061444