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Study identifier: NCT07060261 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma

Condition: Human Papilloma Virus Related Carcinoma · Tonsillar Squamous Cell Carcinoma  ·  Sponsor: Case Comprehensive Cancer Center

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective research study aims to see if pre-operative MRI can predict the margin status after transoral robotic surgery (TORS) for human papillomavirus positive (HPV+) tonsillar squamous cell carcinoma (SCC). The pre-operative MRI will have a standard MR neck without and with contrast, with added axial T2 weighted sequence and T2 SPACE sequence through the tonsils. Three neuroradiologists will grade the thickness of the pharyngeal constrictor muscle (the muscle that surrounds the tonsils) on a five-point scale. The study will determine if the pre-operative MRI grading will correlate with positive, insecure (\<1mm), or secure (\>1mm) margin during TORS surgery for your HPV+ tonsillar SCC.

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan Lee, MD  ·  216-445-9390  ·  LEEJ13@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Case Comprehensive Cancer Center, Cleveland Clinic FoundationCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07060261