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Study identifier: NCT07059234 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Motor Activity - Subjective Energy (MASE) Project

Condition: Depressive Disorder, Major  ·  Sponsor: University of Bern

PhaseNA
Planned participants180
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

This approach utilizes accelerometry to measure NEA and electronic diaries for real-time psychological assessments, overcoming limitations of traditional methods such as retrospective bias and low ecological validity. Brief episodes of physical activity in daily life, which are distinctly different from structured exercise sessions, are generally linked to improved affective well-being. Notably, feelings of energy are particularly associated with incidental, unstructured, and non-exercise activities. Clinically, psychomotor retardation and diminished mood are key diagnostic features of MDD, with evidence suggesting that lower motor activity differentiates MDD patients from controls and that increased activity correlates with treatment response. In this context, the MASE project aims to design personalized BA interventions that focus on increasing NEA and, in turn, enhancing subjective energy levels to reduce depressive symptoms and prevent relapse.

This description comes directly from the study's public registry record.

Talk to the study team

Claudio R. Nigg, Prof  ·  0041316844188  ·  claudio.nigg@unibe.ch

Lea Nitzpon, M.Sc.  ·  0041316845106  ·  lea.nitzpon@unibe.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University of BernBern, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT07059234