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Study identifier: NCT07057297 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study

Condition: Carotid Arteriosclerosis · Carotid Stenosis · Brain Stroke  ·  Sponsor: Charles University, Czech Republic

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

This prospective, multicenter observational study aims to evaluate the incidence, timing, and characteristics of residual and recurrent (restenosis) carotid artery stenosis following carotid endarterectomy (CEA) with primary closure. Conducted across several neurosurgical centers in the Czech Republic, the study will include patients undergoing elective CEA who meet standard clinical indications. Participants will undergo preoperative CT angiography and follow-up imaging at 30 days and 1 year post-surgery. Residual stenosis is defined as ≥50% luminal narrowing detected within 30 days postoperatively, while restenosis is evaluated at later time points. The study will also assess clinical outcomes such as ischemic stroke, TIA, myocardial infarction, and mortality. The standardized surgical technique and harmonized diagnostic algorithm across all centers aim to provide robust data on the performance and durability of primary closure CEA.

This description comes directly from the study's public registry record.

Talk to the study team

norbert Svoboda, MD  ·  +420973202963  ·  norbert.svoboda@uvn.cz

Always discuss trial participation with your own doctor first.

Locations (1)

Central Military Hospital PraguePrague, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07057297