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Study identifier: NCT07056075 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prevention of Desaturations Using Positive Airway Pressure or Capnometry During ERCP

Condition: Desaturation · Hypoxemia · ERCP  ·  Sponsor: Karl Landsteiner University of Health Sciences

PhaseNA
Planned participants288
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

Although sedation during endoscopy is sufficiently safe, desaturations are among the most common side effects of endoscopic retrograde cholangiopancreatography (ERCP) procedures, occurring in approximately 20-30% of cases. Sedation during endoscopy increases the complication rate, and a significant proportion of severe and serious side effects are respiratory/airway-related. However, most patients require sedation to complete the procedure and achieve adequate outcomes during therapeutic ERCP. Therefore, improved measures to increase ERCP safety are needed. Since the demand for anesthesia in many centers already (far) exceeds current capacities, performing additional ERCPs under general anesthesia is not an option. Innovative ways to improve cardiorespiratory monitoring or respiratory management during ERCP could offer a solution without significantly increasing costs. Fortunately, dedicated devices for respiratory management and/or monitoring during endoscopy already exist, but their impact on improving patient safety has not yet been well studied. Therefore, the aim of this prospective, randomized, open-label, non-interventional study is to investigate the effects of non-invasive airway management and respiratory monitoring devices on desaturation rate during endoscopic retrograde cholangiopancreatography. For this purpose, 288 adult patients (male and female, 18+ years) undergoing ERCP for medical reasons will be enrolled and randomized to one of three groups: (i) airway …

This description comes directly from the study's public registry record.

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Locations (2)

Division of Gastroenterology and Hepatology, Department of Medicine, Medical University GrazGraz, AustriaRecruiting
Department of Internal Medicine 2, University Hospital of St PöltenSankt Pölten, AustriaRecruiting

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Source record: clinicaltrials.gov/study/NCT07056075