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Study identifier: NCT07055399 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Iparomlimab and Tuvonralimab Plus Chemotherapy-eclipse for Locally Advanced Cervical Cancer (NICE-CC)

Condition: Locally Advanced Cervical Cancer  ·  Sponsor: Fujian Cancer Hospital

PhasePhase 2
Planned participants43
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

Locally advanced cervical cancer (LACC) remains a significant global health concern with limited treatment options. Recent advancements suggest that using neoadjuvant anti-PD-1 inhibitors in combination with chemotherapy, followed by radical surgery, may be an effective treatment strategy for patients with PD-L1-positive LACC. This study aims to evaluate the efficacy and safety of preoperative treatment with iparomlimab and tuvonralimab-a bifunctional PD-1/CTLA-4 dual blocker-combined with chemotherapy for LACC.

This description comes directly from the study's public registry record.

Talk to the study team

Yang Sun, PHD  ·  86-15959028989  ·  sunyang@fjzlhospital.com

Jie Lin, MD  ·  86-15860818601  ·  linjie@fjzlhospital.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fujian Cancer HospitalFuzhou, Fujian, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07055399