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Study identifier: NCT07053800 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

Condition: Lupus Nephritis  ·  Sponsor: Autolus Limited

PhasePhase 2
Planned participants35
Who can joinAll sexes, 12 Years to 65 Years
Healthy volunteersNo

About this study

The purpose of this trial is to evaluate the efficacy and safety of obecabtagene autoleucel (obe-cel) administered once following lymphodepletion in participants with severe, refractory systemic lupus erythematosus (SLE) and active lupus nephritis (LN).

This description comes directly from the study's public registry record.

Talk to the study team

Autolus Ltd  ·  +44 (0)203 911 4385  ·  clinicaltrials@autolus.com

Always discuss trial participation with your own doctor first.

Locations (12)

State University of New York Upstate Medical Center (SUNY)Syracuse, New York, United StatesRecruiting
Texas Transplant InstituteSan Antonio, Texas, United StatesRecruiting
University General Hospital ATTIKONAthens, GreeceRecruiting
University General Hospital of PatrasPátrai, GreeceRecruiting
Queen Elizabeth Hospital BirminghamBirmingham, United KingdomRecruiting
Bristol Haematology and Oncology CentreBristol, United KingdomRecruiting
Addenbrooke's HospitalCambridge, United KingdomRecruiting
Western General Hospital EdinburghEdinburgh, United KingdomRecruiting
Queen Elizabeth University HospitalGlasgow, United KingdomRecruiting
University College HospitalLondon, United KingdomRecruiting
Great Ormond Street HospitalLondon, United KingdomRecruiting
Manchester Royal InfirmaryManchester, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07053800